The application of an artificial intelligence (AI)-based screening tool for retinal disease in India and Thailand highlighted the myths and reality of introducing medical AI, which may form a framework for subsequent tools
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References
Gulshan, V. et al. JAMA 316, 2402–2410 (2016).
FDA. https://www.fda.gov/media/134754/download (2018).
Krause, J. et al. Ophthalmology 125, 1264–1272 (2018).
Schaekermann, M. et al. Transl. Vis. Sci. Technol. 8, 40 (2019).
Greenland, S. J. Clin. Epidemiol. 41, 1167–1174 (1988).
Abràmoff, M. D. et al. NPJ DigitMed. 1, 39 (2018).
Rajkomar, A. et al. Ann. Intern. Med. 169, 866–872 (2018).
Faes, L. et al. Lancet Digit Health 1, e232–e242 (2019).
Ruamviboonsuk, P. et al. NPJ Digit Med. 2, 25 (2019).
Chia, M. A. et al. Br. J. Ophthalmol. https://doi.org/10.1136/bjo-2022-322237 (2023).
Liu, X. et al. Ophthalmol Retina 6, 398–410 (2022).
Ruamviboonsuk, P. et al. Lancet Digit Health 4, e235–e244 (2022).
Beede, E. et al. in Proc. 2020 CHI Conference on Human Factors in Computing Systems 1–12 (Association for Computing Machinery, 2020).
Pedersen, E. R. et al. NEJM Catalyst https://doi.org/10.1056/CAT.21.0096 (2021).
Feng, J. et al. NPJ Digit Med. 5, 66 (2022).
US FDA, Health Canada & UK MHRA. https://go.nature.com/3negsku (2021).
Azizi, S. et al. Nat. Biomed. Eng. (in the press).
Sellergren, A. B. et al. Radiology https://doi.org/10.1148/radiol.212482 (2022).
Acknowledgements
We thank the Google and Verily teams involved in developing, delivering, and improving ARDA. We also thank to C. Chen and M. Howell for manuscript feedback and A. Iurchenko for the illustration concept. Our work was inspired by our partners continuously expanding access to high quality care such as R. Kim and his team at the Aravind Eye Hospital, P. Ruamviboonsuk and his team at the Rajavithi Hospital in Thailand, and J. Cuadros and his team at EyePACS.
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Widner, K., Virmani, S., Krause, J. et al. Lessons learned from translating AI from development to deployment in healthcare. Nat Med 29, 1304–1306 (2023). https://doi.org/10.1038/s41591-023-02293-9
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DOI: https://doi.org/10.1038/s41591-023-02293-9